Article

Systematic Identification of Germ Granule Proteins Reveals Specialized Roles in RNAi and Small RNA Inheritance

2026-01-28

Abstract excerpt

Biomolecular condensates, such as germ granules, organize RNAi pathways critical for fertility and genome regulation. Yet, the protein composition and functional contributions of these condensates remain poorly defined. Here, we applied TurboID proximity labeling to the Caenorhabditis elegans germ granule protein SIMR-1, integrating mass spectrometry with genetic screening, CRISPR-based tagging, and small RNA seq...

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Literature Corpus work: bc1dc8c5-aa1f-5507-b6f5-c526cb1bb727
DOI: 10.64898/2026.01.26.701902

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