Article

Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis

2022-03-18

Abstract excerpt

Neurodegenerative protein conformational diseases are characterized by misfolding and aggregation of metastable proteins encoded within the host genome. The host is also home to thousands of proteins encoded within exogenous genomes harbored by bacteria, fungi, and viruses. Yet, their contributions to host protein-folding homeostasis, or proteostasis, remain elusive. Recent studies, including our previous work, su...

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Literature Corpus work: ea8469f3-2a40-5804-a48e-873e42dac074
DOI: 10.20944/preprints202203.0267.v1

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