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Article

Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2020

Kapitansky Oxana, Giladi Eliezer, Jaljuli Iman, Bereswill Stefan, Heimesaat Markus M, Gozes Illana

Abstract excerpt

Activity-dependent neuroprotective protein (ADNP) and its protein snippet NAP (drug candidate CP201) regulate synapse formation and cognitive as well as behavioral functions, in part, through microtubule interaction. Given potential interactions between the microbiome and brain function, we now investigated the potential effects of the ADNP-deficient genotype, mimicking the ADNP syndrome on microbiota composition...

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Identifiers

PMID: 32072336
DOI: 10.1007/s00702-020-02155-5
PMCID: PMC7035218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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