Article
Microbiome-Derived Prion-Like Proteins and Their Potential to Trigger Cognitive Dysfunction
2023-10-20
Abstract excerpt
Our life is intricately connected to microorganisms through infection or symbiotic relationships. While the inter-species propagation of prion-like proteins is well-established, their presence in the microbiome and impact on the host remains largely unexplored. To address this, we conducted a systematic study integrating in silico , in vitro, and in vivo analyses, showing that 63% of the gastrointestinal tract...
Topics
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- Alzheimer's disease research and treatments
- Botulinum Toxin and Related Neurological Disorders
- Cannabis and Cannabinoid Research
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Parkinson's Disease Mechanisms and Treatments
- Prion Diseases and Protein Misfolding
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- 13f0685c-4b6e-590f-b482-19b23ddd6331
- DOI
- 10.1101/2023.10.19.563052
