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Multi-Omics profiling of hepatocellular carcinoma reveals prognostic biomarkers, HBV-driven oncogenic networks, and therapeutic vulnerabilities in genomic-immune crosstalk

2025-07-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Hepatocellular carcinoma (HCC) remains a molecularly heterogeneous malignancy with limited therapeutic biomarkers. While transcriptomic studies have identified dysregulated genes, their prognostic relevance, proteomic concordance, and interactions with hepatitis B virus (HBV) mutations remain underexplored. <bold>Methods:</bold> We integrated multi-omics analyse...

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Literature Corpus work
ea5aceac-eda3-56cb-9efa-97b2237e60e2
DOI
10.21203/rs.3.rs-7040990/v1
Open publication

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Multi-Omics profiling of hepatocellular carcinoma reveals prognostic biomarkers, HBV-driven oncogenic networks, and therapeutic vulnerabilities in genomic-immune crosstalkDOI 10.21203/rs.3.rs-7040990/v1
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