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Comprehensive transcriptomic analysis of hepatocellular Carcinoma: Uncovering shared and unique molecular signatures across diverse etiologies

1 Jul 2025

Abstract excerpt

Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, often diagnosed at advanced stages where treatment options are limited. This study undertakes a comprehensive meta-analysis of gene expression profiles from 19 independent datasets sourced from the Gene Expression Omnibus (GEO), encompassing a diverse range of HCC etiologies, including HBV and HCV infections, cirrhosis, and normal liver...

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Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver Disease Diagnosis and Treatment
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40678800
DOI: 10.1016/j.bbrep.2025.102123

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