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Breaking Therapeutic Resistance in Hepatocellular Carcinoma: Systems Biology Deconvolution of the B-cell Microenvironment Identifies PDIA6 as a Novel Target

2026-03-26

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<title>Abstract</title> <p> Background B cells are integral components of the tumor microenvironment (TME) and play a pivotal role in regulating anti-tumor immunity. However, the systematic classification of B-cell-associated molecular features in hepatocellular carcinoma (HCC) and their value in clinical prognosis and immunotherapy remain elusive. Methods We elucidated the molecular characteristics of B cells...

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Literature Corpus work
c2504d7c-83dd-5e84-a336-68c37b63a2f4
DOI
10.21203/rs.3.rs-9213778/v1
Open publication

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Breaking Therapeutic Resistance in Hepatocellular Carcinoma: Systems Biology Deconvolution of the B-cell Microenvironment Identifies PDIA6 as a Novel TargetDOI 10.21203/rs.3.rs-9213778/v1
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