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Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

1 Oct 2019

Abstract excerpt

We performed the first proteogenomic characterization of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) using paired tumor and adjacent liver tissues from 159 patients. Integrated proteogenomic analyses revealed consistency and discordance among multi-omics, activation status of key signaling pathways, and liver-specific metabolic reprogramming in HBV-related HCC. Proteomic profiling identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31585088
DOI: 10.1016/j.cell.2019.08.052

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