Article

Different Purkinje cell pathologies cause specific patterns of progressive ataxia in mice

2023-08-31

Abstract excerpt

<h4>Background</h4> Gait ataxia is one of the most common and impactful consequences of cerebellar dysfunction. Purkinje cells, the sole output neurons of the cerebellar cortex, are often involved in the underlying pathology, but their specific functions during locomotor control in health and disease remain obfuscated. <h4>Objectives</h4> We aimed to describe the effect of gradual adult-onset Purkinje cell degen...

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Literature Corpus work: ea3522b8-44db-53f2-b7e1-32cf1b55ec2c
DOI: 10.1101/2023.08.29.555378

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