Article
High-speed video gait analysis reveals early and characteristic locomotor phenotypes in mouse models of neurodegenerative movement disorders.
Behavioural brain research - 15 Sept 2016
Preisig Daniel F, Kulic Luka, Krüger Maik, Wirth Fabian, McAfoose Jordan, Späni Claudia, Gantenbein Pascal, Derungs Rebecca, Nitsch Roger M, Welt Tobias
Abstract excerpt
Neurodegenerative diseases of the central nervous system frequently affect the locomotor system resulting in impaired movement and gait. In this study we performed a whole-body high-speed video gait analysis in three different mouse lines of neurodegenerative movement disorders to investigate the motor phenotype. Based on precise computerized motion tracking of all relevant joints and the tail, a custom-developed...
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