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Article

Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors.

PloS one - 1 Jan 2016

Caetano-Anollés Kelsey, Rhodes Justin S, Garland Theodore, Perez Sam D, Hernandez Alvaro G, Southey Bruce R, Rodriguez-Zas Sandra L

Abstract excerpt

The role of the cerebellum in motivation and addictive behaviors is less understood than that in control and coordination of movements. High running can be a self-rewarding behavior exhibiting addictive properties. Changes in the cerebellum transcriptional networks of mice from a line selectively bred for High voluntary running (H) were profiled relative to an unselected Control (C) line. The environmental...

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Identifiers

PMID: 27893846
DOI: 10.1371/journal.pone.0167095
PMCID: PMC5125674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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