Article

Identification of gene fusions associated with amyotrophic lateral sclerosis

2022-06-06

Abstract excerpt

Genetics is an import risk factor for amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease affecting motor neurons. Recent findings demonstrate that, in addition to specific genetic mutations, structural variants caused by genetic instability can also play a causative role in ALS. Genomic instability can lead to deletions, duplications, insertions, inversions, and translocations in the geno...

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Literature Corpus work: ea2ed330-f54a-5b06-9973-8a4f3d13ddf2
DOI: 10.1101/2022.06.04.22275962

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