Article

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

2021-09-01

Abstract excerpt

<h4>Background</h4> Gene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making requires high confidence and precision of detection. Recent developments show RNA sequencing (RNA-seq) is promising for genome-wide detection of fusion products, but hindered by many false positives that require extensive manual curation...

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Literature Corpus work: 925dfe17-be81-5838-a98d-35792b14c836
DOI: 10.1101/2021.08.31.458342

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