Article

The First Insight into the Hereditary Fusion Gene Landscape of Amyotrophic Lateral Sclerosis

2023-03-17

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a progressive nervous system disease that causes loss of muscle control. Over 30 mutated genes are associated with ASL. However, 90-95% of ASL cases have been found without a family history. Here, we have analyzed RNA-Seq data of NYGC ALS Consortium and identified fusion transcripts from ASL patients and non-neurologic controls (NNC). In this study, we combined previously-cur...

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Literature Corpus work: 69a72464-93ec-5c7f-a2a9-1b3f92a5a884
DOI: 10.1101/2023.03.14.23287250

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