Article

SFyNCS detects oncogenic fusions involving non-coding sequences in cancer

2023-04-06

Abstract excerpt

Fusion genes are well-known cancer drivers. However, very few known oncogenic fusions involve non-coding sequences. We develop SFyNCS with superior performance to detect fusions of both protein-coding genes and non-coding sequences from transcriptomic sequencing data. We validate fusions using somatic structural variations detected from the genomes. This allows us to comprehensively evaluate various fusion detecti...

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Literature Corpus work: dab4bc32-723c-5b29-927f-06355399a011
DOI: 10.1101/2023.04.03.535462

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