Article

A G-quadruplex structure at the 5′ end of the H19 coding region regulates H19 transcription

2017-04-03

Abstract excerpt

The H19 gene, one of the best known imprinted genes, encodes a long non-coding RNA that regulates cell proliferation and differentiation. H19 RNA is widely expressed in embryonic tissues, but its expression is restricted in only a few tissues after birth. However, regulation of H19 gene expression remains poorly understood outside the context of genomic imprinting. Here we identified evolutionarily conserved guani...

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Literature Corpus work: e9ffc5db-a8e1-5eb3-9cfa-1b89d9ee6437
DOI: 10.1038/srep45815

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