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Article

H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia.

Clinical epigenetics - 1 Jan 2018

Zhang Ting-Juan, Zhou Jing-Dong, Zhang Wei, Lin Jiang, Ma Ji-Chun, Wen Xiang-Mei, Yuan Qian, Li Xi-Xi, Xu Zi-Jun, Qian Jun

Abstract excerpt

Background: The long non-coding RNA H19 plays a crucial role in solid tumor initiation and progression. However, the potential role of H19 and its clinical significance in acute myeloid leukemia (AML) remain largely elusive. Methods: H19 expression was detected by qPCR, and clinical significance in AML patients was further analyzed. The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) data for AML...

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Share to DNA (Cytosine-5-)-Methyltransferases
Share to DNA Methyltransferase 3A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to fms-Like Tyrosine Kinase 3

Share to Gene Expression Regulation, Leukemic

Share to HL-60 Cells

Share to Leukemia, Myeloid, Acute

Share to RNA, Long Noncoding

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Source

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Identifiers

PMID: 29643943
DOI: 10.1186/s13148-018-0486-z
PMCID: PMC5891930

Genes

FLT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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