Article
H19 lncRNA: Roles in tumorigenesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2020
Ghafouri-Fard Soudeh, Esmaeili Mohammadhosein, Taheri Mohammad
Abstract excerpt
H19 is a long non-coding RNA [lncRNA] which was firstly described as an oncofetal transcript. The imprinted gene is normally expressed from the maternal allele. However, this pattern of imprinting is dysregulated in several cancers leading to aberrant up-regulation of H19 in malignant tissues. Several studies have utilized this aberrant expression pattern to find specific biomarkers for detection of cancer in...
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