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Article

Biological and Clinical Relevance of H19 in Colorectal Cancer Patients

1 Nov 2016

Abstract excerpt

Numerous studies have reported H19, the first discovered long non-coding RNA (lncRNA), to have key regulatory functions in tumor development and progression (Brannan et al., 1990). This paternally imprinted gene is located close to the telomeric region of chromosome 11p15.5 that frequently harbors genetic alterations in tumors. The activities of H19 are diverse, and include genetic and epigenetic mechanisms....

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PMID: 27840010
DOI: 10.1016/j.ebiom.2016.11.001

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