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Article

Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus.

Human molecular genetics - 1 Aug 1996

Jinno Y, Sengoku K, Nakao M, Tamate K, Miyamoto T, Matsuzaka T, Sutcliffe J S, Anan T, Takuma N, Nishiwaki K, Ikeda Y, Ishimaru T, Ishikawa M, Niikawa N

Abstract excerpt

We have identified a region with characteristics of a paternal-specific methylation imprint at the human H19 locus. This region, extending from -2.0 kb upstream to the start of transcription, is heavily methylated in sperm and on the paternal allele in somatic cells. This methylation was preserved during pre-implantation. Structural analysis revealed the presence of CpG islands and a large direct repeat with a...

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PMID: 8842735
DOI: 10.1093/hmg/5.8.1155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus.PMID 8842735Read ↗

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