Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus.

doi:10.1093/hmg/5.8.1155

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Article

Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus.

Human molecular genetics - 1 Aug 1996

Jinno Y, Sengoku K, Nakao M, Tamate K, Miyamoto T, Matsuzaka T, Sutcliffe J S, Anan T, Takuma N, Nishiwaki K, Ikeda Y, Ishimaru T, Ishikawa M, Niikawa N

Abstract excerpt

We have identified a region with characteristics of a paternal-specific methylation imprint at the human H19 locus. This region, extending from -2.0 kb upstream to the start of transcription, is heavily methylated in sperm and on the paternal allele in somatic cells. This methylation was preserve...

Topics

Alleles
Animals
Base Sequence
CpG Islands
DNA
DNA Methylation
DNA Primers
Embryonic Development
Evolution, Molecular
Female
Genes, Tumor Suppressor
Genomic Imprinting
Humans
Male
Mice

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Muscle Proteins

Placenta

Source

Open in PubMed

Identifiers

PMID: 8842735
DOI: 10.1093/hmg/5.8.1155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8842735-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.