Article

Integral Gene Drives: an “operating system” for population replacement

2018-06-27

Abstract excerpt

First generation CRISPR-based gene drives have now been tested in the laboratory in a number of organisms including malaria vector mosquitoes. A number of challenges for their use in the area-wide genetic control of vector-borne disease have been identified. These include the development of target site resistance, their long-term efficacy in the field, their molecular complexity, and the practical and legal limita...

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Literature Corpus work: e9e6375e-b478-57fa-85b0-2fa3e055b67f
DOI: 10.1101/356998

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