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Article

Gene drives gaining speed.

Nature reviews. Genetics - 1 Jan 2022

Bier Ethan

Abstract excerpt

Gene drives are selfish genetic elements that are transmitted to progeny at super-Mendelian (>50%) frequencies. Recently developed CRISPR-Cas9-based gene-drive systems are highly efficient in laboratory settings, offering the potential to reduce the prevalence of vector-borne diseases, crop pests and non-native invasive species. However, concerns have been raised regarding the potential unintended impacts of...

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Identifiers

PMID: 34363067
DOI: 10.1038/s41576-021-00386-0
PMCID: PMC8344398

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