Article

Decoding the variant-to-function relationship for <i>LIPA</i> , a risk locus for coronary artery disease

2022-11-15

Abstract excerpt

Translating human genomic discoveries into mechanistic insights requires linking genetic variations to candidate genes and their causal functional phenotypes. Genome-wide association studies have consistently identified LIPA as a risk locus for coronary artery disease (CAD), with previous expression quantitative trait loci (eQTL) analyses prioritizing LIPA as a candidate causal gene. However, functional studies...

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Literature Corpus work: e9dd8caa-412b-5c23-a483-d3285bf8a1dd
DOI: 10.1101/2022.11.12.516293

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