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Article

From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

Circulation research - 19 Feb 2016

Nurnberg Sylvia T, Zhang Hanrui, Hand Nicholas J, Bauer Robert C, Saleheen Danish, Reilly Muredach P, Rader Daniel J

Abstract excerpt

Genome-wide association studies have provided a rich collection of ≈ 58 coronary artery disease (CAD) loci that suggest the existence of previously unsuspected new biology relevant to atherosclerosis. However, these studies only identify genomic loci associated with CAD, and many questions remain even after a genomic locus is definitively implicated, including the nature of the causal variant(s) and the causal...

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Source

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Identifiers

PMID: 26892960
DOI: 10.1161/CIRCRESAHA.115.306464
PMCID: PMC4863243

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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