Article

Multi-ancestry transcriptome-wide association studies of cognitive function, white matter hyperintensity, and Alzheimer’s disease

2024-01-04

Abstract excerpt

Genetic variants increase the risk of neurocognitive disorders in later life including Vascular Dementia (VaD) and Alzheimer’s disease (AD), but the precise relationships between genetic risk factors and underlying disease etiology are not well understood. Transcriptome-wide association studies (TWAS) can be leveraged to better characterize the genes and biological pathways underlying genetic influences on disease...

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Literature Corpus work: e99a7441-9154-5b33-96b6-0d0688457a39
DOI: 10.1101/2024.01.03.24300768

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