Article

Genomic analyses reveal new insights into Alzheimer's disease

2025-10-13

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia, with global case numbers projected to reach 153 million in 2050. AD is highly heritable, with twin-based heritability estimates of 60-80%. While 1,200 causal loci are predicted to exist for AD, approximately 80 have been associated with AD in two recent studies, suggesting that many loci remain to be discovered. Here, we analyzed data from 109,479 case...

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Literature Corpus work: 4f112cf2-db3f-5377-855e-64e8fae01716
DOI: 10.1101/2025.10.10.25337470

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