Article

Old Age Drives Fusion and Expansion of Vitellogenin Vesicles in the Intestine of <i>Caenorhabditis elegans</i>

2022-07-22

Abstract excerpt

Some of the most conspicuous aging phenotypes of C. elegans are related to post-reproductive production of vitellogenins (Vtg), which form yolk protein (YP) complexes after processing and lipid loading. Vtg/YP levels show huge increases with age, and inhibition of this extends lifespan, but how subcellular and organism-wide distribution of these proteins changes with age has not been systematically explored. Here...

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Literature Corpus work: ebf02642-af7c-5734-9e54-4dd4b1d477b5
DOI: 10.1101/2022.07.21.501051

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