Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of the mitochondrial respiratory chain on longevity in C. elegans.

Experimental gerontology - 1 Aug 2014

Dancy Beverley M, Sedensky Margaret M, Morgan Philip G

Abstract excerpt

How an organism ages is a question that has fascinated biologists, and the elderly, for centuries. One useful approach to understanding complex processes such as aging is to study genetic variation in model organisms such as the nematode, Caenorhabditis elegans. Classical mutant strains and RNAi screens have demonstrated that mitochondrial function is a major factor affecting longevity. Recent advances in the...

Topics

Age Factors
Aging
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Electron Transport Chain Complex Proteins
Energy Metabolism
Genotype
Longevity
Mitochondria
Mitochondrial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Animal

Phenotype

Source

Identifiers

PMID: 24709342
DOI: 10.1016/j.exger.2014.03.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of the mitochondrial respiratory chain on longevity in C. elegans.PMID 24709342Read ↗

Mitochondrial respiration and reactive oxygen species in C. elegans.Semantic proximity Read ↗

Mitochondrial changes in ageing Caenorhabditis elegans--what do we learn from superoxide dismutase knockouts?Semantic proximity Read ↗

Mitochondrial respiration and reactive oxygen species in mitochondrial aging mutants.Semantic proximity Read ↗

The role of mitochondria in the life of the nematode, Caenorhabditis elegans.Semantic proximity Read ↗

Genetics of lifespan in C. elegans: molecular diversity, physiological complexity, mechanistic simplicity.Semantic proximity Read ↗

A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans.Semantic proximity Read ↗

Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damage.Semantic proximity Read ↗

The paradox of mitochondrial dysfunction and extended longevity.Semantic proximity Read ↗

The effects of complex I function and oxidative damage on lifespan and anesthetic sensitivity in Caenorhabditis elegans.Semantic proximity Read ↗

Metabolism in the Caenorhabditis elegans Mit mutants.Semantic proximity Read ↗

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.