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<i>Caenorhabditis elegans</i> reproductive aging: Regulation and underlying mechanisms

24 Nov 2010

Abstract excerpt

Female reproductive decline is one of the first aging phenotypes in humans, manifested in increasing rates of infertility, miscarriage, and birth defects in children of mothers over 35. Recently, Caenorhabditis elegans (C. elegans) has been developed as a model to study reproductive aging, and several studies have advanced our knowledge of reproductive aging regulation in this organism. In this review, we...

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PMID: 21105070
DOI: 10.1002/dvg.20694

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