Article

Oocyte mitochondria link maternal environment to offspring phenotype

2025-05-16

Abstract excerpt

During oogenesis and maturation oocytes undergo a recently discovered mitochondrial electron transport chain (ETC) remodeling in flies 1 , frogs 1 , and humans 2 . This conserved oocyte ETC remodeling is regulated by maternal insulin signaling, but its role in biology remains unclear. In the model animal Caenorhabditis elegans , we previously found that insulin signaling to oocytes regulates offspring’s abilit...

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Literature Corpus work: d4dbf08a-e6f0-5c27-a6e8-efe02197fbbb
DOI: 10.1101/2025.05.13.653493

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