Article

A novel multisystem approach uncovers conserved mitochondrial complex I disease phenotypes and suppressors

2026-08-11

Abstract excerpt

<title>Abstract</title> <p> Mitochondriopathies are a large group of pathological conditions characterized by dysfunction of tissues and organs with high energy needs such as the brain, heart, and skeletal muscles, which highly rely on functional mitochondrial oxidative phosphorylation (OXPHOS). The vast majority of these disorders are ascribed to mutations in nuclear or mitochondrial encoded subunits of complex...

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Literature Corpus work: d099d02b-d199-5a82-8d68-0ba679b3a344
DOI: 10.21203/rs.3.rs-10539896/v1

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