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Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes <i>in vitro</i>

2024-10-29

Abstract excerpt

Myeloid cells including brain-resident (microglia) and peripheral macrophages play a crucial role in various pathological conditions, including neurodegenerative disorders like Alzheimer’s disease (AD). They respond to disruption of tissue homeostasis associated with disease conditions by acquiring various transcriptional and functional states. Experimental investigation of these states is hampered by the lack of...

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Literature Corpus work
e919c057-c6f8-51bd-bf48-47f6255c871b
DOI
10.1101/2024.10.24.619910
Open publication

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Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes <i>in vitro</i>DOI 10.1101/2024.10.24.619910
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