Article

GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling

2020-10-01

Abstract excerpt

Macrophages are central mediators of immunity that integrate diverse signals derived from differentiation cues, tissue location, and disease. Controlling macrophage state and function is an appealing therapeutic objective across many diseases including cancer, atherosclerosis, and tuberculosis. Despite the growing appreciation for the in vivo complexity of macrophage state, existing in vitro models of human mono...

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Literature Corpus work: 73380068-1b19-5770-a780-4fe129fc735e
DOI: 10.1101/2020.09.29.318352

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