Article

Modulation of translational elongation by montanine alkaloids preferentially inhibits RNA viruses

2025-12-20

Abstract excerpt

Montanine, an Amaryllidaceae alkaloid, has demonstrated superior antiviral activity against dengue virus (DENV), SARS-CoV-2, vesicular stomatitis Indiana virus (VSV-G), and vesicular stomatitis virus pseudotyped with Ebola virus glycoprotein (VSV-ZGP), outperforming other antiviral alkaloids tested, including lycorine, narciclasine, tetracetylnarciclasine, and pancracine. We further showed that montanine inhibits...

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Literature Corpus work: e8cf1c47-99b5-551b-8654-39fafe6f2038
DOI: 10.64898/2025.12.19.695327

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