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Ribosomopathies and cancer: pharmacological implications

3 Jun 2022

Abstract excerpt

Introduction The ribosome is a ribonucleoprotein organelle responsible for protein synthesis, and its biogenesis is a highly coordinated process that involves many macromolecular components. Any acquired or inherited impairment in ribosome biogenesis or ribosomopathies is associated with the development of different cancers and rare genetic diseases. Interference with multiple steps of protein synthesis has been...

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PMID: 35787725
DOI: 10.1080/17512433.2022.2098110

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