Back to search

Article

6′,6′-Difluoro-aristeromycin is a potent inhibitor of MERS-coronavirus replication

2021-05-21

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the lack of treatments to combat infections with human or (potentially) zoonotic CoVs. Thus, it is critical to develop and evaluate antiviral compounds that either directly target CoV functions or modulate host functions involved in viral replication. Here, we demonstrate that low-micromolar concentrations of 6′,6′-difluoro-a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
278f8364-ac98-5078-86d1-683e734f0344
DOI
10.1101/2021.05.20.445077
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
6′,6′-Difluoro-aristeromycin is a potent inhibitor of MERS-coronavirus replicationDOI 10.1101/2021.05.20.445077
Select a neighboring publication to make it the new centre.