Article

The role of Lipoprotein(a) and oxidized phospholipids in modifying the effects of aspirin on major cardiovascular events and bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) randomized clinical trial: Statistical analysis plan

2026-05-20

Abstract excerpt

<h4>ABSTRACT</h4> Lipoprotein(a) (Lp(a)) is associated with atherothrombosis through several mechanisms, including putative antifibrinolytic properties. In the ASPREE randomized trial of daily low-dose aspirin for primary prevention in older adults, 72% of trial participants in Australia provided baseline blood samples from which Lp(a) and related oxidized phospholipids and plasminogen have been measured in a spe...

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Literature Corpus work: e8aeb8fa-e67d-51ac-aa6b-8f2c0cc55d15
DOI: 10.64898/2026.05.17.26353443

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