Article
Lipoprotein(a) and prothrombotic effects: Evidence from a genetic association study.
European journal of internal medicine - 1 May 2025
Olmastroni Elena, Katzmann Julius L, Galimberti Federica, Laufs Ulrich, Catapano Alberico L
Abstract excerpt
BACKGROUND: It is unknown whether lipoprotein(a) [Lp(a)] has prothrombotic effects contributing to its association with the risk of myocardial infarction (MI). METHODS: In 410,177 participants of UK Biobank, associations of LPA genetic variants and observed Lp(a) concentrations with the risk of venous thromboembolism (VTE) and MI were investigated, stratified by scores of genetic variants influencing coagulation...
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