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Article

Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes.

Journal of the American College of Cardiology - 4 Oct 2022

Lacaze Paul, Bakshi Andrew, Riaz Moeen, Polekhina Galina, Owen Alice, Bhatia Harpreet S, Natarajan Pradeep, Wolfe Rory, Beilin Lawrence, Nicholls Stephen J, Watts Gerald F, McNeil John J, Tonkin Andrew M, Tsimikas Sotirios

Abstract excerpt

BACKGROUND: The role of aspirin in reducing lipoprotein(a)-mediated atherothrombotic events in primary prevention is not established. OBJECTIVES: This study sought to assess whether low-dose aspirin benefits individuals with elevated plasma lipoprotein(a)-associated genotypes in the setting of primary prevention. METHODS: The study analyzed 12,815 genotyped individuals ≥70 years of age of European ancestry and...

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Identifiers

PMID: 36175048
DOI: 10.1016/j.jacc.2022.07.027
PMCID: PMC10025998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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