Lipoprotein(a), platelet function and cardiovascular disease.

doi:10.1038/s41569-023-00947-2

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Article

Lipoprotein(a), platelet function and cardiovascular disease.

Nature reviews. Cardiology - 1 May 2024

Bhatia Harpreet S, Becker Richard C, Leibundgut Gregor, Patel Mitul, Lacaze Paul, Tonkin Andrew, Narula Jagat, Tsimikas Sotirios

Abstract excerpt

Lipoprotein(a) (Lp(a)) is associated with atherothrombosis through several mechanisms, including putative antifibrinolytic properties. However, genetic association studies have not demonstrated an association between high plasma levels of Lp(a) and the risk of venous thromboembolism, and studies in patients with highly elevated Lp(a) levels have shown that Lp(a) lowering does not modify the clotting properties of...

Topics

Humans
Blood Coagulation
Cardiovascular Diseases
Lipoprotein(a)
Polymorphism, Single Nucleotide
Risk Factors

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Identifiers

PMID: 37938756
DOI: 10.1038/s41569-023-00947-2
PMCID: PMC11216952

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