Article
Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy.
Atherosclerosis - 1 Apr 2009
Chasman Daniel I, Shiffman Dov, Zee Robert Y L, Louie Judy Z, Luke May M, Rowland Charles M, Catanese Joseph J, Buring Julie E, Devlin James J, Ridker Paul M
Abstract excerpt
OBJECTIVE: A minor allele variant (rs3798220) of apolipoprotein(a) has been reported to be associated with elevated plasma lipoprotein(a) [Lp(a)] and increased cardiovascular risk. We investigated whether this allele was associated with elevated Lp(a) and cardiovascular risk in the Women's Health Study, a randomized trial of low-dose aspirin, and whether aspirin reduced cardiovascular risk in minor allele...
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