Article

Distinct and sequential re-replication barriers ensure precise genome duplication

2018-07-10

Abstract excerpt

Achieving complete and precise genome duplication requires that each genomic segment be replicated only once per cell division cycle. Protecting large eukaryotic genomes from re-replication requires an overlapping set of molecular mechanisms that prevent the first DNA replication step, the DNA loading of MCM helicase complexes to license replication origins. Previous reports have defined many such origin licensing...

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Literature Corpus work: e87679e9-0197-5417-b71e-52d42e19a81b
DOI: 10.1101/366666

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