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Article

The role of the replication licensing system in cell proliferation and cancer.

Progress in cell cycle research - 1 Jan 2003

Shreeram S, Blow J Julian

Abstract excerpt

The precise duplication of chromosomal DNA during each cell cycle is essential for the maintenance of genetic stability. Failure to correctly regulate chromosomal DNA replication could lead to losses or duplication of chromosome segments. The precise duplication of chromosomes is normally achieved by correct regulation of the replication licensing system. Here we review our current knowledge of the licensing...

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Identifiers

PMID: 14593723
PMCID: PMC3604915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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