Article

Trehalose metabolism and its impact on PrfA activity in <i>Listeria monocytogenes</i>

2026-05-07

Abstract excerpt

Listeria monocytogenes can grow as a saprophyte on decaying plant material, but can also switch to a pathogenic lifestyle. This switch is mediated by the virulence regulator PrfA, which activates the expression of most virulence genes. PrfA activity is tightly regulated by several mechanisms to ensure that virulence genes are only expressed within the host. One of these regulatory mechanisms is the sugar-dependent...

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Literature Corpus work: e85f40c5-fdc8-526d-8f88-345c59965da3
DOI: 10.64898/2026.05.05.722976

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