Article
Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA.
Molecular microbiology - 1 Mar 2003
Milohanic Eliane, Glaser Philippe, Coppée Jean-Yves, Frangeul Lionel, Vega Yolanda, Vázquez-Boland José A, Kunst Frank, Cossart Pascale, Buchrieser Carmen
Abstract excerpt
PrfA is the major regulator of Listeria virulence gene expression. This protein is a member of the Crp/Fnr family of transcription regulators. To gain a deeper understanding of the PrfA regulon, we constructed a whole-genome array based on the complete genome sequence of Listeria monocytogenes strain EGDe and evaluated the expression profiles of the wild-type EGDe and a prfA-deleted mutant (EGDe Delta prfA). Both...
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