Article
Hpt, a bacterial homolog of the microsomal glucose- 6-phosphate translocase, mediates rapid intracellular proliferation in Listeria.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2002
Chico-Calero Isabel, Suárez Mónica, González-Zorn Bruno, Scortti Mariela, Slaghuis Jörg, Goebel Werner, Vázquez-Boland José A
Abstract excerpt
Efficient replication in vivo is essential for a microparasite to colonize its host and the understanding of the molecular mechanisms by which microbial pathogens grow within host tissues can lead to the discovery of novel therapies to treat infection. Here we present evidence that the foodborne bacterial pathogen Listeria monocytogenes, a facultative intracellular parasite, exploits hexose phosphates (HP) from...
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