Article

Rv3400 is a phosphoglucomutase required for trehalose metabolism in <i>Mycobacterium tuberculosis</i>

2025-11-20

Abstract excerpt

Mycobacterium tuberculosis is a global killer causing over a million deaths from tuberculosis (TB) every year. It is therefore a major burden on human health. To reduce the deadly impact of TB, we need a better understanding of the strategies used by M. tuberculosis to adapt its metabolism to survive and persist in the human host. This will help us design better strategies for TB treatment and control. Previous e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 24df7867-595d-5c7a-9551-e6f30c7d0701
DOI: 10.1101/2025.11.20.689507

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rv3400 is a phosphoglucomutase required for trehalose metabolism in <i>Mycobacterium tuberculosis</i>DOI 10.1101/2025.11.20.689507Read

Phosphoglucomutase A mediated regulation of carbon flux is essential for antibiotic and disease persistence in <i>Mycobacterium tuberculosis</i>Semantic proximity Read

Targeting trehalose and methylglucose lipopolysaccharide biosynthetic pathways in M. tuberculosis : structural and functional characterisation, and early-stage drug discovery of OtsA and Rv3030Semantic proximity Read

Identification of M. tuberculosis Rv3441c and M. smegmatis MSMEG_1556 and essentiality of M. smegmatis MSMEG_1556.Semantic proximity Read

The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapiesSemantic proximity Read

Underestimated Manipulative Roles of Mycobacterium tuberculosis Cell Envelope Glycolipids During InfectionSemantic proximity Read

Genetics of Mycobacterial Trehalose MetabolismSemantic proximity Read

Exquisite specificity of Pks13 defines the essentiality of trehalose in mycobacteriaSemantic proximity Read

Proteomic analysis of <i>Mycobacterium tuberculosis</i> lacking a putative short-chain dehydrogenase (Rv0148)Semantic proximity Read

A new stress-response pathway in <i>Mycobacterium tuberculosis</i>Semantic proximity Read

The Rv0805 Gene from <i>Mycobacterium tuberculosis</i> Encodes a 3‘,5‘-Cyclic Nucleotide Phosphodiesterase: Biochemical and Mutational AnalysisSemantic proximity Read

Genetic and metabolic regulation of <i>Mycobacterium tuberculosis</i> acid growth arrestSemantic proximity Read

Delineating the functional role of the <i>PPE50 (Rv3135) - PPE51 (Rv3136)</i> gene cluster in the pathophysiology of <i>Mycobacterium tuberculosis</i>Semantic proximity Read