Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trehalose-6-phosphate-mediated phenotypic change in Acinetobacter baumannii.

Environmental microbiology - 1 Dec 2020

Hubloher Josephine Joy, Zeidler Sabine, Lamosa Pedro, Santos Helena, Averhoff Beate, Müller Volker

Abstract excerpt

The stress protectant trehalose is synthesized in Acinetobacter baumannii from UPD-glucose and glucose-6-phosphase via the OtsA/OtsB pathway. Previous studies proved that deletion of otsB led to a decreased virulence, the inability to grow at 45°C and a slight reduction of growth at high salinities indicating that trehalose is the cause of these phenotypes. We have questioned this conclusion by producing ∆otsA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acinetobacter baumannii
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glucosyltransferases

Share to Hot Temperature

Share to Phosphoric Monoester Hydrolases

Share to Sodium Chloride

Share to Sugar Phosphates

Share to Trehalose

Source

Identifiers

PMID: 32618111
DOI: 10.1111/1462-2920.15148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trehalose-6-phosphate-mediated phenotypic change in Acinetobacter baumannii.PMID 32618111Read ↗

Trehalose-deficient Acinetobacter baumannii exhibits reduced virulence by losing capsular polysaccharide and altering membrane integrity.Semantic proximity Read ↗

Effects of NaCl Concentrations on Growth Patterns, Phenotypes Associated With Virulence, and Energy Metabolism in Escherichia coli BW25113Semantic proximity Read ↗

Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus.Semantic proximity Read ↗

The repression of trehalose transport and metabolism in Escherichia coli by high osmolarity is mediated by trehalose-6-phosphate phosphatase.Semantic proximity Read ↗

Trehalose and α-glucan mediate distinct abiotic stress responses in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Synthesis, accumulation, and excretion of trehalose in osmotically stressed Escherichia coli K-12 strains: influence of amber suppressors and function of the periplasmic trehalase.Semantic proximity Read ↗

RpoE2 of Sinorhizobium meliloti is necessary for trehalose synthesis and growth in hyperosmotic media.Semantic proximity Read ↗

Role of trehalose in salinity and temperature tolerance in the model halophilic bacterium Chromohalobacter salexigens.Semantic proximity Read ↗

Role of trehalose in growth at high temperature of Salmonella enterica serovar Typhimurium.Semantic proximity Read ↗

Pentose Phosphate Pathway Protects <i>E. coli</i> from Antibiotic LethalitySemantic proximity Read ↗

Trehalose biosynthesis in Thermus thermophilus RQ-1: biochemical properties of the trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase.Semantic proximity Read ↗

Metabolic phenotypes of Saccharomyces cerevisiae mutants with altered trehalose 6-phosphate dynamics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.