Article
How seryl-phosphorylated HPr inhibits PrfA, a transcription activator of Listeria monocytogenes virulence genes.
Journal of molecular microbiology and biotechnology - 1 Jan 2005
Herro Rana, Poncet Sandrine, Cossart Pascale, Buchrieser Carmen, Gouin Edith, Glaser Philippe, Deutscher Josef
Abstract excerpt
Listeria monocytogenes PrfA, a transcription activator for several virulence genes, including the hemolysin-encoding hly, is inhibited by rapidly metabolizable carbon sources (glucose, fructose, etc.). This inhibition is not mediated via the major carbon catabolite repression mechanism of gram-positive bacteria, since inactivation of the catabolite control protein A (CcpA) did not prevent the repression of...
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