Article

Low nanomolar Triiodothyronine Concentrations Drive Further Maturation of hiPSC-Derived Hepatocyte-Like Cells

2025-05-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> The increasing prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) highlights the need for improved in vitro models to study disease mechanisms and therapeutic interventions. Thyroid hormones (TH) are key regulators of hepatic carbohydrate and lipid metabolism, and their reduced availability is implicated in MASLD pathogenesis. While hu...

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Literature Corpus work: e85877bc-f338-5084-9449-debb6621bbe1
DOI: 10.21203/rs.3.rs-6595009/v1

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